November 30, 2010

Caleco Pharma Corp. Files Amendment To EU Patent Office Application

PRESS RELEASE

Nov. 30, 2010, 9:04 a.m. EST

Amendments Strengthens Proposed Claims Relating to Compounds Exhibiting Anti-Viral Activity

LONG VALLEY, NEW JERSEY, Nov 30, 2010 (MARKETWIRE via COMTEX) -- Caleco Pharma Corp. ("Caleco") /quotes/comstock/11k!caeh (CAEH 0.06, -0.02, -20.00%) (frankfurt:T3R)(wkn:A0N9Y0) (www.calecopharmacorp.com), a diversified healthcare company with biopharmaceutical and consumer health product development programs that develop products derived from natural sources such as plant extracts, today reports that it has amended its intellectual property (IP) filing with the European Patent Office in The Hague to further secure and strengthen Caleco's anti-viral pipeline.

In response to the EU Patent Office's Examination Report, Caleco reports that the company's European Patent Application number 08725530.3 is amended with regard to compositions comprising derivatives and derivative combinations of Lamiridosin and Iridoid for treatment of Hepatitis C. The molecular specifications required in these amendments resulted in the exclusion of certain derivative claims. However, these claims will not be abandoned, but instead, these claims will be pursued through one or more divisional applications.

John Boschert, Caleco's CEO, said, "By amending our filing we are seeking to solidify our intellectual property position in the billion dollar Hepatitis C and anti-viral marketplace. We plan to continue to pursue a broader pipeline of semi-synthetic derivatives that will be prepared for further testing in 2011. The Hepatitis C patient population remains greatly underserved by existing treatment options and we are eager to move these compounds into the next stage of development."

About Caleco Pharma Corp.

Caleco is focused on the ongoing research and development of its pipeline of over-the-counter and prescription medications including its proprietary antiviral and "Liver Health" OTC formulations. In addition Caleco is developing Dermatological Products based on the active ingredients found in its proprietary formulation. Caleco's intellectual property covering the Liver Health formulations and derivatives consists of patent applications in the United States, Europe and Canada and four European Drug Master File applications.

Caleco's shares are traded in the United States on the OTC Bulletin Board /quotes/comstock/11k!caeh (CAEH 0.06, -0.02, -20.00%) and in Germany on the Frankfurt Stock Exchange (frankfurt:T3R)(wkn:A0N9Y0).

This press release may contain, in addition to historic information, forward-looking statements. These statements may involve known and unknown risks and uncertainties and other factors that may cause the actual results to be materially different from the results implied herein. In particular, there are no assurances that: (i) the United States Patents and Trademarks Office and the European Union Patent office will grant Caleco a patent in connection with its current patent applications; (ii) Caleco will be able to manufacture and produce its products or that its products will be effective; (iii) Caleco Pharma Europe will be able to successfully distribute Lamiridosin in Europe; (iv) Caleco will be able to carry out any pre-clinical or clinical trials of its products; (v) Caleco will be able to obtain additional financing in order to meet the costs of the clinical studies of the "Liver Health" formulation; and (vi) Caleco will be able to control the costs of the clinical studies of the "Liver Health" formulation. Readers are cautioned not to place undue reliance on the forward-looking statements made in this press release.

Contacts:

BlueWater Advisory Group - Investor Relations
Bryan Crane
Managing Director
805-426-5090
ir@calecopharma.com
http://www.calecopharmacorp.com/

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