Posted on the OSN SuperSite October 25, 2010
Arch Ophthalmol. 2010;128(10):1295-1299.
The prevalence of hepatitis C infection may be relevant to ocular adnexal non-Hodgkin lymphoma, and hepatitis C may influence the initial appearance of the disease, a study said.
In the retrospective comparative study, medical records of 129 patients with ocular adnexal non-Hodgkin lymphoma were reviewed.
The prevalence of hepatitis C virus (HCV) infection among the patients was 17.8%, and seropositivity for infection was significantly associated with extraorbital lymphoma at the onset, the study said.
A high prevalence of mucosa-associated lymphoid tissue disease (79.8%) was also noted.
Ninety-nine patients who underwent radiotherapy and chemotherapy achieved complete remission, while 23.6% of patients with HCV-seronegative status and 21.7% of patients with HCV-seropositive status relapsed.
"However, the overall and disease-free survival of the infected patients are not statistically different than that of patients who are not infected," the authors said.