Showing posts with label Alcoholism. Show all posts
Showing posts with label Alcoholism. Show all posts

February 4, 2014

Alcohol-linked deaths a problem for the Americas

Elizabeth DeVita-Raebrun
Reuters
3:05 p.m. CST, February 4, 2014

NEW YORK (Reuters Health) - Liver disease and brain disorders due to alcohol abuse are important causes of premature death in the Americas, a new study concludes.

The toll of too much drinking is especially high among men and among middle-aged people, according to the report, whose authors say it's the first to tabulate deaths resulting solely from alcohol.

"This provides direct evidence of the impact of alcohol on the health of countries in the region," said one of the study's authors, Dr. Vilma Pinheiro Gawryszewski, an advisor on health information and analysis for the Pan American Health Organization(PAHO).

In the 16 North, Central, and South American countries studied, alcohol was the sole cause of 79,456 deaths a year, the researchers say. That represented 1.4 percent of deaths from all causes, and alcohol-related liver disease alone accounted for 0.6 percent of all-cause mortality.

The study was based on data collected between 2007 and 2009 for countries in the PAHO mortality database.

The researchers excluded deaths from vehicle accidents and other fatal situations where alcohol might have been involved but there could also have been other causes.

Looking just at deaths due directly to alcohol, they found 63 percent were from liver disease and 32 percent were from neurological and psychiatric conditions grouped under "degeneration of the brain and nervous system."

Other listed causes of death included alcohol poisoning, alcohol-linked heart and gastric problems and fetal alcohol syndrome.

The death toll is the "tip of the iceberg," meaning that there are probably many more alcohol-related deaths that the researchers were not able to identify, said another of the study's authors, Dr. Maristela Monteiro, regional advisor on alcohol and substance abuse at PAHO.

Monteiro said that raising the price of alcohol and increasing taxes would help to prevent some of these deaths. Many countries have found these steps effective in controlling tobacco use, but such measures have not been used to control alcohol consumption, she said.

Even the U.S., which was included in the study, has not done as much as it could, said David Jernigan, director of the Center on Alcohol Marketing and Youth at Johns Hopkins Bloomberg School of Public Health.

"The single most efficient thing you can do is to raise taxes," Jernigan told Reuters Health. "Many states haven't raised it in decades. That means the price doesn't go up with inflation, and alcohol gets cheaper every year."

And while the U.S. and other countries have limited tobacco advertising, alcohol advertising "is virtually everywhere," he said.

Mortality due to alcohol was highest in El Salvador, Guatemala and Nicaragua, with death rates of 27.4, 22.3 and 21.3 per 100,000 people, respectively. These were also the countries with the highest consumption of hard liquor, the authors noted.

Colombia, Argentina and Canada had the lowest death rates attributable to alcohol at 1.8, 4.0 and 5.7 per 100,000, respectively. The alcohol death rate in the United States was "intermediate," at 6.7 per 100,000, Monteiro said.

Men accounted for 84 percent of the deaths overall, but that proportion was not the same in all countries. The risk of a man dying from alcohol in El Salvador was nearly 30 times higher than that of a woman, but only about three times higher in Canada and the U.S.

People in the mid-to-late 50s and 60s age range were at the highest risk. This later in life risk, Jernigan said, points to the long-term impact of heavy drinking.

"Mostly in this country, we talk about alcohol and the risk for the young," in whom drunk driving, violence, and accidents are important causes of death, Jernigan said. "This really shows the impact over the life course."

Despite the grim statistics, Jernigan says studies like this one are a positive sign.

"On one hand, you could say, 'this is a huge problem, and not enough is being done.' On the other," he said, "you could say, 'we're getting better at documenting it and showing that, until we take meaningful action, it's not going to go away.'"

In poorer countries, other factors contributing to the deaths could include infectious diseases that hasten the course of liver disease, as well as poor nutrition and limited access to health services.

"In the U.S., people wouldn't wait until they were too sick for help to seek out services, because treatment is available," said Monteiro. That is not always the case, she said, in other countries.

Source: http://bit.ly/1enwJIT Addiction, online January 14, 2014.

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January 8, 2014

Most U.S. doctors fail to discuss alcohol with patients: study

BY DAVID BEASLEY

ATLANTA Tue Jan 7, 2014 2:53pm EST

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Bottles showing the barrel aging process are seen at the Jack Daniel's distillery in Lynchburg, Tennessee May 10, 2011.

CREDIT: REUTERS/ MARTINNE GELLER

(Reuters) - Doctors are failing to find out if their patients drink too much alcohol, despite evidence that at least 38 million American adults consume an excessive amount, a U.S. health agency said on Tuesday.

An estimated 88,000 people die in the United States each year from drinking too much alcohol, but only one out of six adults overall and one in four binge drinkers have discussed their drinking habits with their doctors, according to a new study by the Centers for Disease Control and Prevention (CDC).

That practice needs to change, CDC Director Thomas Frieden said.

"It should be a part of routine patient care," Frieden said. "In the same way we screen patients for high blood pressure, high cholesterol, we should be screening for excess alcohol use."

The study's findings were based on 166,000 interviews in 44 states and the District of Columbia in 2011. The percentage of patients who had ever discussed their drinking with a health care provider ranged from a low of 8.7 percent in Kansas to 25.5 percent in Washington, D.C.

Doctors are often too busy to screen patients for alcohol abuse and may view treatment options as ineffective, the CDC said.

But asking patients about their alcohol use and then offering advice on how to reduce it, or referring the most serious cases for specialized treatment, can be effective in many cases, Frieden said.

"Counseling for five, 10, 15 minutes can result in a substantial reduction in problem drinking," he said.

Drinking too much can increase chances of heart disease, liver damage, breast cancer and other health problems, the CDC said.

The CDC defines binge drinking as five or more drinks in a few hours for men and four or more for women. Adult men should average no more than two drinks a day and women no more than one daily, the health agency said.

The federal Affordable Care Act of 2010 requires new insurance plans to cover alcohol screening with no patient co-pay, Frieden said.

(Editing by Colleen Jenkins and Chris Reese)

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December 19, 2013

Protein links liver cancer with obesity, alcoholism, and hepatitis

PUBLIC RELEASE DATE:19-Dec-2013

Contact: Jennifer Brown
jennifer-l-brown@uiowa.edu
Public Library of Science

A new study identifies an unexpected molecular link between liver cancer, cellular stress, and risk factors for developing this cancer – obesity, alcoholism, and viral hepatitis. In the study by University of Iowa researchers and published in the journal PLOS Genetics, researchers show that a protein called CHOP, which had previously been thought to generally protect against cancer, actually promotes liver cancer in mice.

Obesity, alcoholism, and chronic hepatitis all increase the risk of getting liver cancer, the third leading cause of cancer death worldwide. There are few good treatment options for advanced liver cancer and rates of the disease have doubled in the U.S. in the past 20 years, driven in part by increasing obesity.

Obesity, alcoholism, and viral hepatitis also cause cellular stress and induce expression of CHOP, a transcription factor that is known to promote cell death. The study shows that in mice, despite its role in cell death, CHOP is actually elevated in cancerous liver cells. Furthermore, mice without CHOP are partially protected from liver cancer, developing fewer and smaller tumors than the normal mice in response to liver cancer-causing drugs. Tissue samples from human patients show that CHOP is also elevated in human liver tumors compared to surrounding non-tumor tissue from the same patients.

Having implicated CHOP as a contributing factor in liver cancer associated with obesity, alcoholism, and hepatitis, the UI team plans to identify the other proteins that partner with CHOP to promote liver cancer. A better understanding of this biological pathway may lead to targets for therapies to better treat liver cancer.

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October 27, 2013

Alcoholism is a complicating factor for women with hepatitis C

By Tele management

Alcohol

TeleManagement) Women with hepatitis C lose survival advantage over men if they drink heavily.
Hepatitis C is a chronic infection of the liver which is passed on through contaminated blood and often linked with drug use. It sometimes leads to severe liver damage and liver cancer. Previous research has suggested that hepatitis C progresses more slowly among women, giving them a survival advantage. Drinking, to the point of alcoholism, on the other hand, worsens the outcome.

Researchers for the National Institute on Alcohol Abuse and Alcoholism put together these trends to look at the outcome for women with both hepatitis C and alcoholism. They analyzed 132,468 deaths related to hepatitis C or alcoholism. Women with hepatitis C who were not heavy drinkers died at an average age of 61. Those women with both hepatitis C and alcoholism died at an average age of 49. For men, the corresponding average ages at death were 55 and 50 years. Therefore, alcoholism wipes out the gender advantage women have over men when it comes to survival from hepatitis C. The researchers admit the study has one limitation – alcoholism often precludes access to treatment for hepatitis C because those affected are less likely to benefit. This may be a contributing factor to the lower survival rates seen when hepatitis C and alcoholism are combined.

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